치아우식 예방을 위한 치아미백기의 활용 : 광역동 치료로서의 접근
Application of Teeth Whitening LED for Prevention of Dental Caries : Antimicrobial Photodynamic Therapy Approach
박초아, 박호원, 이주현, 서현우, 이시영,
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박초아 ( Park Cho-A ) - Gangneung-Wonju National University College of Dentistry Department of Pediatric Dentistry
박호원 ( Park Ho-Won ) - Gangneung-Wonju National University College of Dentistry Department of Pediatric Dentistry
이주현 ( Lee Ju-Hyun ) - Gangneung-Wonju National University College of Dentistry Department of Pediatric Dentistry
서현우 ( Seo Hyun-Woo ) - Gangneung-Wonju National University College of Dentistry Department of Pediatric Dentistry
이시영 ( Lee Si-Young ) - Gangneung-Wonju National University College of Dentistry Department of Oral Microbiology
Abstract
The present study is aimed to assess the effect of antimicrobial photodynamic therapy (aPDT) on Streptococcus mutans biofilm through teeth whitening light emitting diode (LED). Planktonic and dynamic biofilm state cultures of S. mutans were used. Erythrosine 20 μM/L was used as the photosensitizer. Irradiation was performed by exposing cultures to clinic and homecare whitening LEDs for 15 minutes. The viability was measured through Colony Forming Unit counts and confocal laser scanning microscopy. aPDT using whitening LEDs and erythrosine significantly decreased the CFU count of S. mutans compared to that in the control group. Dynamic biofilm group showed more resistant features to aPDT compared with planktonic state. Clinic and homecare whitening LED device showed similar antimicrobial effect. The whitening LED, which could irradiate the entire oral arch, showed a significant photodynamic effect on cariogenic S. mutans biofilm. aPDT mediated by erythrosine and LEDs used for teeth whitening exhibited promising antimicrobial activity.
키워드
Photodynamic therapy; Whitening LED; Erythrosine; Streptococcus mutans
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